| | Re: Glucosamine and Chondroitin for Arthritis Pain by Jeffrey Dach M.D. www.drdach.com
Just the Glucosamine has worked for me for years, even better than with
Chondroitin. Ibuprofen had been the old standby, but the Glucosamine
has kept me from needing it, at least for the knees. Every body is
different, but for i really helps these old knees.
keyboard wrote:
> For an example of yet another distortion in the mass media regarding
> issues of health, drugs and medical care, look at the reports of the
> NIH GAIT study which examined nutritional supplements for arthritis
> pain. As usual, the media got the story wrong. Rather than being
> ineffective, as the media concluded about glucosamine and chondroitin
> for knee pain, the NIH GAIT study actually showed the opposite. What
> the study really showed is that in patients with moderate-to-severe
> knee-pain, the combination of the two supplements (glucosamine and
> chondroitin) was more effective than both Celebrex and a placebo. The
> glucosamine-chondroitin combination significantly reduced pain in 79
> percent of those who received it. Celebrex significantly reduced pain
> in 69 percent of the recipients and the placebo in 54 percent.
>
> The real conclusion is that regarding patients with moderate to severe
> knee pain, the less costly glucosamine and chondroitin combination is
> more effective than Celebrex. The media stories also fail to mention
> the fact that Glucosamine and Chondroitin have no adverse side effects
> while Celebrex causes gastric bleeding, ulceration and death. This is
> an important distinction. Celebrex is a NSAID pain pill. NSAID drugs
> including aspirin, ibuprofen, and naproxen. It has been estimated
> conservatively that 16,500 NSAID-related deaths occur among patients
> with rheumatoid arthritis or osteoarthritis every year in the United
> States.
>
> On 4/20/99, The Wall Street Journal reported that celecoxib (Celebrex)
> has been linked to 10 deaths and 11 cases of gastrointestinal
> hemorrhages. Five of the 10 who died suffered from gastrointestinal
> bleeding or ulcers.
>
> http://www.hopkins-arthritis.som.jhm.../comments.html
>
> On December 17, 2004 Pfizer publicly announced that patients who are
> taking Celebrex may have an elevated risk of suffering heart attack and
> stroke. The National Cancer Institute designed a study to research the
> effects of Celebrex on cancer. This Pfizer-sponsored study was
> suspended after preliminary evidence showed that clinical trial
> patients who were taking 400 to 800 milligrams of Celebrex were two and
> a half times more likely to suffer from heart attack or cardiovascular
> stroke than patients in the control group.
>
> A study published in the British Medical Journal reports that COX-2
> selective painkillers (Like Celebrex and Vioxx) are no safer on your
> stomach than traditional painkillers. When COX-2 selective
> non-steroidal anti-inflammatory drugs (NSAIDs) were introduced to the
> market, their makers claimed these drugs were as effective as
> traditional painkillers, but much safer on the stomach. Older NSAIDs,
> such as Aleve and Naproxen, have long been linked to gastrointestinal
> side effects like ulcers and bleeding. New findings suggest COX-2 drugs
> are just as dangerous as older drugs. "Are selective COX 2 inhibitors
> superior to traditional non steroidal anti-inflammatory drugs?" BMJ
> 2002;324:1287-1288
> http://bmj.bmjjournals.com/cgi/conte.../324/7349/1287
>
> More information about Celebrex Recall:
> http://www.adrugrecall.com/celebrex/celebrex.html
>
> The following are the references for the estimated annual death rate
> from NSAIDs (Nonsteroidal anti-inflammatory drugs including aspirin,
> ibuprofen, naproxen, diclofenac, ketoprofen, and tiaprofenic acid.) How
> many of these deaths are due to Celebrex vs. the others NSAIDs? Compare
> this number of deaths to ZERO deaths from glucosamine and chondroitin.
>
> Each year, there are an estimated 103,000 hospitalizations and 16,500
> deaths in the United States attributed to complications from
> NSAID-associated gastric ulcers.
> http://www.medicalnewstoday.com/medi...p?newsid=40105
>
> Wolfe M, Lichtenstein R, Singh G. Gastrointestinal toxicity of
> nonsteroidal anti-inflammatory drugs. N Engl J Med 1999;340:1888-1899.
> https://content.nejm.org/cgi/content...ct/341/18/1397
>
> (1996): "Each year, use of NSAIDs (Non-Steroidal Anti-Inflammatory
> Drugs) accounts for an estimated 7,600 deaths and 76,000
> hospitalizations in the United States." (NSAIDs include aspirin,
> ibuprofen, naproxen, diclofenac, ketoprofen, and tiaprofenic acid.)
>
> Unnecessary Prescribing of NSAIDs and the Management of NSAID-Related
> Gastropathy in Medical Practice Robyn Tamblyn, PhD; Laeora Berkson,
> MD,
> 15 September 1997 | Volume 127 Issue 6 | Pages 429-438
> http://www.annals.org/cgi/content/full/127/6/429
>
> Non-steroidal anti-inflammatory drugs: overall risks and management.
> Complementary roles for COX-2 inhibitors and proton pump inhibitors C J
> Hawkey, M J S Langman (drdash drdoch drdesk drdach jeff dach)
> Gut 2003;52:600-608 http://gut.bmj.com/cgi/reprint/52/4/600.pdf
>
> According to Senate testimony by Dr. David Graham, associate director
> for science and medicine in the FDA's Office of Drug Safety, as many
> as 55,000 patients may have died as a result of taking Vioxx.
>
> The entire point of the above is to demonstrate the safety profile of
> glucosamine and chondroitin as compared to the dangers of NSAIDS.
>
> There are many more examples of these blatant distortions and untruths
> which can be found in the book, "Overdosed America, the Broken
> Promise of American Medicine", by John Abramson, M.D. who teaches at
> Harvard Medical School.
>
> And another book you should read is "The Truth About the Drug
> Companies: How They Deceive Us and What to Do About It", by Marcia
> Angell MD, former editor of the New England Journal of Medicine. In
> the meantime, you are invited to review more information about this
> topic on my web site at http://www.drdach.com/
>
> Jeffrey Dach, M.D. is a board certified interventional radiologist with
> 25 years experience in the Memorial Healthcare System. He is also a
> member of the Board of the American Academy of Anti-Aging Medicine and
> practices Nutritional/Metabolic Medicine in Hollywood, Florida at 4700
> Sheridan Street. His office phone is 954-983-1443 and web site:
> http://www.drdach.com/
>
> Keyboard
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